I agree on this, r_picmip 16 looks very nice.
Did you do all the usual things, like removing unneeded background programs, or verifying that you don't have viruses, or maybe disabling/changing your antivirus software?
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Just for the record, picmip only goes up to 10, but for some reason it's listed as going up to 16. There's no visible changes between picmip 10 and picmip 16. (I still use 16 though :P)